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Date registered: May 14, 2011

Latest posts

  1. Holmes, AI — January 29, 2022
  2. FDA Run Control Specification(Part 9) — February 7, 2020
  3. Paddling Outrigger Canoe in Hawaii — October 21, 2019
  4. FDA Validation of Companion Diagnostic (PCR test) — November 27, 2018
  5. Creating Your Own Personal Silent Retreat — September 1, 2018

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Holmes, AI

A Sherlock Holmes story with machine learning. Learn: scikit-learn, a machine learning library Image Analysis Face Recognition Google’s Colaboratory Python Notebook


FDA Run Control Specification(Part 9)

Sometimes the specifications initially set are too restrictive, because not enough runs have been done to capture the variability of the experiment. In run control specification, we rerun the statistics on all the validation runs to establish more liberal thresholds.


Paddling Outrigger Canoe in Hawaii

Singapore waters are warm all-year-round, so even on Christmas day we can paddle. However, Singapore lacks waves (except for those generated by the occasional ferry passing by). I love the rush from surfing waves — you feel like you’re flying. So a year ago, my partner asked for an OC paddling vacation to surf waves.  …

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FDA Validation of Companion Diagnostic (PCR test)

I’ve been helping get a companion diagnostic get approved as a FDA test. This blog series will describe the statistics (R) used for the FDA validation of the companion diagnostic. The companion diagnostic test is a PCR test to check for a fusion / rearrangement on the customer’s DNA. Normally, people have gene A and …

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Creating Your Own Personal Silent Retreat

I was seeking silence and solitude so I spent a few days at Bali Silent Retreat. It was an ascetic vegetarian lifestyle (which was a bit much for me). While I had my moments of revelation, I realized I didn’t have to fly to Indonesia for silence. This blog post will describe how to create …

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Fantasy and Genetics – Do They Go Together Like Science and Fiction?

This could be a disaster. I’m launching a new website that does genetic analyses for fun. It combines make-believe and science. There are a lot of direct-to-consumer genetics products out there, yet genetics is not very predictive at the individual level. The science behind these difficulties is abtruse, so why not have some fun while helping people understand …

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Obsessions in Alzheimer’s

This video shows a woman with Alzheimer’s who is obsessed with finding and helping a non-existent cat. The obsession happens over a two-month period and you can tell she’s very distressed. She is always looking for a cat — wandering the streets and even breaking windows to go out and find this cat. Her daughter …

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Can’t lose weight with Belviq?

With the holidays nearly over, I have to admit I’m feeling sick overeating with the holiday parties and goodies given as gifts. We’ll be examining the gender differences in the weight loss drug Belviq (generic name lorcaserin). Based on online ratings, Belviq works better in males than in females (men gave 1.18 more points for …

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Treating depression: Wellbutrin is more effective for females than males.

Millions suffer from depression, so it’s important to know which treatments work. Women are underrepresented in clinical trials. Thus, it is possible that they react differently to drugs. To study this, we downloaded online drug reviews to see if women responded to drugs differently than men. Surprisingly, women rated Wellbutrin XL higher than males. Wellbutrin …

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Lighting a Path Forward

About 2 years ago, I accidentally wrote a children’s book. (Accidentally is a strange word: rather, I never intended to write a children’s book, but when an idea sticks with me, the only way to get it out of my head is to do it.) My significant other is part of a company that makes …

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